Mutram

Strengths

Mutram 50, Mutram 100, Mutram 150, Mutram 200

Dosage Form

Sustained Release Film Coated Tablets

Composition

Mutram 50
Each S.R.F.C.Tablet contains:
Tramadol 50 mg

Mutram 100
Each S.R.F.C.Tablet contains:
Tramadol 100 mg

Mutram 150
Each S.R.F.C.Tablet contains:
Tramadol 150 mg

Mutram 200
Each S.R.F.C.Tablet contains:
Tramadol 200 mg

Packaging

Mutram 50: 30 S.R.F.C.Tablets
Mutram100: 30 S.R.F.C.Tablets
Mutram150: 30 S.R.F.C.Tablets
Mutram 200: 30 S.R.F.C.Tablets

Indications

Treatment of moderate to severe pain

Dosage and Administration

The dose should be adjusted to the intensity of the pain and the sensitivity of the individual patient. The lowest effective dose for analgesia should generally be selected. The total daily dose of 400 mg active substance should not be exceeded, except in special circumstances.
Unless otherwise prescribed, Tramadol SR should be administered as follows:
Adults and adolescents above the age of 12 years:
The usual initial dose is 50-100 mg tramadol hydrochloride twice daily, morning and evening. If pain relief is insufficient, the dose may be titrated upwards to 150 mg or 200 mg tramadol hydrochloride twice daily.
Children:
Tramadol SR is not suitable for children below the age of 12 years.
Geriatric patients:
A dose adjustment is not usually necessary in patients up to 75 years without clinically manifest hepatic or renal insufficiency. In elderly patients over 75 years elimination may be prolonged. Therefore, if necessary the dosage interval is to be extended according to the patient's requirements.
Renal insufficiency/dialysis and hepatic insufficiency:
In patients with renal and/or hepatic insufficiency the elimination of tramadol is delayed. In these patients prolongation of the dosage interval should be carefully considered according to the patients requirements. In cases of severe renal and/or severe hepatic insufficiency Tramadol SR prolonged-release tablets are not recommended.
Method of administration:
The tablets are to be taken whole, not divided or chewed, with sufficient liquid, independent of meals.
Duration of administration:
Tramadol should under no circumstances be administered for longer than absolutely necessary. If long-term pain treatment with tramadol is necessary in view of the nature and severity of the illness, then careful and regular monitoring should be carried out (if necessary with breaks in treatment) to establish whether and to what extent further treatment is necessary.